The impact of Perioperative Dexmedetomidine usage in prevention of Acute Kidney Injury in patients undergoing Whipple operations
Phase 4
Recruiting
- Conditions
- Anaesthesia
- Registration Number
- PACTR202408886014501
- Lead Sponsor
- national liver institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Adult patients (18 years or older) undergoing Whipple surgery.
Exclusion Criteria
Patients with pre-existing renal dysfunction (eGFR <60 mL/min/1.73 m2)
Major intraoperative events (e.g. severe hemodynamic instability, massive blood loss, massive blood products transfusion).
Allergy to Dexmedetomidine, unwilling to participate in the study will be excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method renal function tests urea and creatinine
- Secondary Outcome Measures
Name Time Method rine output in the first 24 hours postoperatively.<br>Incidence of delirium, hypotension, bradycardia, and prolonged mechanical ventilation within 48 hours postoperatively<br>