Implementation and Evaluation of Tailored Interventions to Increase MMR and/or HPV Vaccine

Not Applicable

Not yet recruiting

• Conditions: Vaccination; Health Systems; Knowledge, Attitudes, Practice

• Registration Number: NCT06361628
• Lead Sponsor: University Medical Center Groningen

Brief Summary

The goal of the study is to monitor and evaluate the implementation of interventions that aim to increase HPV \& MMR vaccines among underserved communities across four European countries: Greece, Netherlands, Poland, and Slovakia. The interventions will target identified health systems barriers in an earlier phase of the project. The interventions that will be implemented employ trusted community members as health promotors whom will provide educational sessions on HPV and MMR vaccination to the target groups. In addition, the cost-effectiveness of vaccine uptake strategies for the target groups is being evaluated.

The main research question is: to what extent is the multicomponent tailored intervention effective to increase MMR/HPV intention and vaccine uptake in the target population in Greece, Netherlands, Poland and Slovakia?

Detailed Description

The general objective of the study is to improve access to vaccination by addressing relevant system level barriers to increase HPV and MMR (where applicable) vaccine intention and uptake among the target groups. The investigators expect that the intervention will address health system barriers to improve increase in access to information on vaccination and vaccination services.

A prospective multicomponent intervention study will be performed between 1st of April 2024 and 31st of July 2025 that will be evaluated using a pre and post design as well as a participatory approach during the implementation. As part of the multicomponent intervention a preparatory phase is taken place before this period of time. The multicomponent intervention consists of training of health promotors and healthcare professionals, and of educational sessions to community members and navigation. The educational sessions will be offered at suitable and accessible locations for the target population.

The five communities targeted in are the following:

1. The migrant community in Greece (HPV and MMR)

2. Turkish and Moroccan women in the Netherlands (HPV)

3. The Ukrainian community in Poland (HPV and MMR)

4. The Roma community in Slovakia (HPV)

Study Timeline

• Study First Submitted: 2024-03-20
• Status Verified: 2024-04
• Study First Submitted QC: 2024-04-09
• Study First Posted: 2024-04-12
• Last Update Submitted: 2024-04-15
• Last Update Posted: 2024-04-17
• Study Start: 2024-05-01
• Primary Completion: 2025-06-01
• Study Completion: 2025-06-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• parents of children eligible for MMR and/or HPV vaccination according to country guidelines on those specific vaccines

Exclusion Criteria

• respondents not willing or able to fill out questionnaires

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Intention to vaccinate MMR and/or HPV by questionnaire	Pre and immediately following the intervention and 6 month post intervention	Intention for vaccination against MMR and/or HPV among the underserved communities

Secondary Outcome Measures

Name	Time	Method
Uptake of MMR and/or HPV vaccinations by questionnaire	Pre and 6 month post intervention evaluation is necessary	MMR and/or HPV vaccination uptake among the underserved communities
Communication skills of health care professionals using a questionnaire	Pre intervention and directly post intervention	Communication skills of healthcare professionals to deliver appropriate information
Satisfaction of the stakeholders as measured by a questionnaire	Directly post intervention	Satisfaction of stakeholders (health promotors and health professionals) with the implementation process and the intervention itself
Knowledge concerning MMR and/or HPV vaccinations in the target group using a questionnaire	Pre and immediately following the intervention and 6 month post intervention evaluation	Knowledge concerning MMR and/or HPV vaccinations among the target group

Trial Locations

Locations (4)

Prolepsis; 🇬🇷 Athens, Athene, Greece

University Medical Center Groningen; 🇳🇱 Groningen, Netherlands

University of Zielona Gora; 🇵🇱 Zielona Góra, Lubusz, Poland

PJ Šafárik University; 🇸🇰 Košice, Košice Region, Slovakia