NCT05681325Unknown不适用
Evaluation of Antioxidant and Anti-inflammatory Effect of Matcha Tea Intake on Periodontal Health
Hayder Raad Abdulbaqi1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年1月25日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- change in salivary level of ant-inflammatory marker
研究概览
简要总结
Aim of the study:
This study aims to evaluate the antioxidant and beneficial effects of matcha tea daily intake on periodontal health.
Objectives:
- To evaluate the salivary level of antioxidants (catalase, total antioxidant capacity) after matcha tea intake compared to green tea over a period of one month.
- To evaluate the clinical periodontal parameters including bleeding on probing (BOP), probing pocket depth (PPD) and plaque index (PI) after matcha tea intake compared to green tea over a period of one month.
- To evaluate the salivary levels of IL-1B after matcha tea intake compared to green tea over a period of one month.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •• having at least 20 teeth,
- •underwent no medical treatment during the last 3 months before examination and sampling,
- •non-smoker,
- •no history of systemic disease,
- •gingivitis patient (having >10% bleeding sites with no PPD >3 mm).
排除标准
- •• wore orthodontic appliances,
- •pregnant or currently in the breast-feeding period,
- •periodontitis patient,
- •has a history of systemic disease.
研究组 & 干预措施
matcha tea group
Experimental
Jade Leaf Organic Japanese Matcha, USA. It will be given 2 cups / day for 30 days.
干预措施: matcha tea (Dietary Supplement)
green tea group
Active Comparator
Mahmood Green Tea Sri Lanka. It will be given 2 cups / day for 30 days.
干预措施: green tea (Dietary Supplement)
结局指标
主要结局
change in salivary level of ant-inflammatory marker
时间窗: 30 Days (baseline to one moth of tea intake)
change in level of interleukin- one beta (IL-1B) in pg/L
change in salivary level of antioxidant marker
时间窗: 30 Days (baseline to one moth of tea intake)
change in level of catalase enzyme in ku/L
次要结局
- change in percentage of bleeding on probing (BOP)(30 Days (baseline to one moth of tea intake))
- change in plaque index (PI) scores(30 Days (baseline to one moth of tea intake))
研究者
Hayder Raad Abdulbaqi
professor
University of Baghdad
研究点 (1)
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