Oral Contraceptive and Strength Training

Not Applicable

Completed

• Conditions: Healthy

• Registration Number: NCT03374878
• Lead Sponsor: University of Aarhus

Brief Summary

Cross sectional study investigating the effect of strength training in users and non-users of oral contraceptives (OC) (2nd generation OC)

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-12-05
• Study First Submitted QC: 2017-12-11
• Study First Posted: 2017-12-15
• Study Start: 2018-02-01
• Status Verified: 2018-06
• Primary Completion: 2019-01-01
• Study Completion: 2019-01-01
• Last Update Submitted: 2019-09-24
• Last Update Posted: 2019-09-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 38

Inclusion Criteria

• 18.5 - 30 years
• BMI < 30

Exclusion Criteria

• Medicine influencing protein turnover
• Surgery on the knee
• Arthritis
• Diabetes
• Smoking
• irregular menstruation (<24 days or >35 days cycles)
• Non-users: not have used contraceptives for the last 3 months.
• Unstable weight (+/- 5 kg within the last 6 months)
• Regular training/exercise more than 2 hours/week for the last 6 months. Maximum 70 km of cycling transport/week.
• Strength training >1time/month for the last 6 months.
• Pregnancy
• Diet og eating disorder
• Can not read or understand danish

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Muscle mass	Baseline + after 10 weeks of resistance training.	Change in muscle mass determined by MRI scan of thigh muscle

Secondary Outcome Measures

Name	Time	Method
Muscle fiber size	Baseline + after 10 weeks of resistance training.	Change in muscle fiber cross sectional area measured by histology.
Functionality	Baseline + after 10 weeks of resistance training.	Change in jump performance by RSI (Reactive strength index) measures
Blood values	Baseline + after 10 weeks of resistance training.	Change in sex hormone profile measured by blood sample analysis
Fat free mass (FFM)	Baseline + after 10 weeks of resistance training.	Change in FFM measured by dual energy x-ray absorptiometry (DXA) scan of whole body composition
Muscle strength	Baseline + after 10 weeks of resistance training.	Change in isometric strength

Trial Locations

Locations (1)

Aarhus University, Department for Public Health, Section for Sport Science; 🇩🇰 Aarhus, Denmark