Influence of Oral Contraceptive Use on Recovery in Trained Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Changes in maximal knee extensor strength and Rate of force development
研究概览
简要总结
There is still no one who has studied how oral contraceptive use affects recovery in trained women after repeated high-intensity workouts. Consequently, a well-controlled study is needed.
The project is designed as a controlled cohort study, where 20 oral contraceptive users will be compared with 20 non-users. After initial preliminary examination and habituation to the test procedures, the subjects will start the intervention in week 2 of their menstrual cycle / active contraceptive pill cycle. Before and 3h, 24h and 48h after 3 intense strength training sessions performed 2 days in a row, blood samples will be taken, muscle soreness measured and performance tests performed. The day before the first training session and over the 4 trial days, the subjects will receive a standardized diet.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •BMI 18.5-30
- •Regular training minimum. 4 times a week (1≤ times strength training, 1≤ times endurance training / interval training or interval-based sports. If the interest in participation is greater than necessary, we will prioritize people who perform strength training at least twice a week)
排除标准
- •Irregular menstruation over the last 6 months (shorter than 24 days or longer than 35 days cycle)
- •Used birth control pills for less than 6 months
- •Non-birth control pill users must not have used birth control pills, IUDs, birth control pills, or mini- pills for a maximum of 1 month during the last 6 months and not within the last 3 months up to the trial. .
- •Injuries / pain in the lower body, which prevents participation in intense strength training
- •Medication consumption that may affect protein metabolism and inflammatory parameters.
- •Unstable weight / major weight loss (weight fluctuations of more than 5 kg in the last six months)
- •Eating disorder
- •Pregnancy
- •Cannot read or understand Danish
结局指标
主要结局
Changes in maximal knee extensor strength and Rate of force development
时间窗: Before, 3 hours , 24 hours and 48 hours after training
Measured in a Humac Norm dynamometer
次要结局
- Changes in Wingate performance(Before, 3 hours , 24 hours and 48 hours after training.)
- Changes in Yoyo-intermittent recovery 1 performance(Before, and 48 hours after training.)
- Changes training volume(Before, 3 hours , 24 hours and 48 hours after training.)
- Differences in knee laxity(Baseline)
- Changes in Leg press performance(Before, 3 hours , 24 hours and 48 hours after training.)
- Changes in muscle soreness (VAS-score)(Before, 3 hours , 24 hours and 48 hours after training)
- Changes in Jumping performance(Before, 3 hours , 24 hours and 48 hours after training.)
- Blood analysis: Sex hormones, cortisol, inflammatory markers and markers of muscle damage(Before, 3 hours , 24 hours and 48 hours after training)