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Microfluidic embryo culture.

Recruiting
Registration Number
NL-OMON26411
Lead Sponsor
VUmc (VU University Medical Center)
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
400
Inclusion Criteria

Frozen-thawed donated human embryos of sufficient morphological quality will be included in the study. The following criteria have to be met after thawing:

1. Minimum number of blastomeres: 8 cells;

Exclusion Criteria

Embryos with insufficient morphological quality after thawing will be excluded from the study according to the criteria described above.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The main study endpoint is the blastocyst formation rate on day 5, 28 hours after thawing, in both, the control and experimental group.
Secondary Outcome Measures
NameTimeMethod
The secondary study parameter is the morphology of each embryo at different time points. The percentage of embryos that reach each developmental stage will be recorded and analysed as secondary study endpoints. Furthermore we will assess how many embryos are suitable for embryo transfer one day after thawing according to standard laboratory criteria.
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