Beta-cell function and autoantibody patterns in long-standing type 1 diabetes

• Conditions: E10; Type 1 diabetes mellitus

• Registration Number: DRKS00034682
• Lead Sponsor: Klinikum Karlsburg, Herz- und Diabteszentrum Mecklenburg-Vorpommern

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-07-30
• Study Start: 2024-07-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

Diabetes mellitus Type 1
Diabetes duration longer than 30 years
Insulin therapy since diabetes manifestation
Blood glucose on the day of the examination 4-11 mmol/l

Exclusion Criteria

eGFR < 60 ml/min
Pregnancy

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Increase of plasma C-Peptid during Mixed Meal Tolerance Test

Secondary Outcome Measures

Name	Time	Method
Positivity for diabetes autoantibodies (GADA, IA-2A, ZnT8A)