Effect of different application regimes of tranexamic acid on perioperative blood loss in total knee arthroplasty

• Conditions: M17; Gonarthrosis [arthrosis of knee]

• Registration Number: DRKS00017095
• Lead Sponsor: Orthopädische Klinik König-Ludwig-Haus

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 1254

Inclusion Criteria

Primary total knee arthroplasty under the use of tranexamic acid

Exclusion Criteria

none

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Estimated perioperative blood loss using pre- and postoperative lab values

Secondary Outcome Measures

Name	Time	Method
Acute postoperative pain intensity (numeric rating scale 0-10) and mobility (range of motion, walking skills) assessed by the hospital's physiotherapists who were completely blinded to the application regime of tranexamic acid. <br>Long-term follow up by PROMS (WOMAC-Score) after 3 and 12 months.