To compare the effectiveness of oral tablets of tranexamic acid and vitamin C versus injections of tranexamic acid and vitamin C over face in patients with melasma
Phase 4
- Conditions
- Health Condition 1: L818- Other specified disorders of pigmentation
- Registration Number
- CTRI/2024/01/061709
- Lead Sponsor
- Dr RPGMC Tanda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients of melasma presenting consecutively in the outdoor clinic of Department of Dermatology, Venerology & Leprosy of Dr. R.P.G.M.C, Kangra at Tanda, Himachal Pradesh
Exclusion Criteria
1) Pregnant and lactating women
2) Patients taking oral contraceptives
3) Patients with prior history of thromboembolism, bleeding disorders, and abnormal coagulogram
4) Patients with psychological disorders
5) Patients with active herpetic lesions or warts on face
6) Patients having over expectation from the treatment
7) Patients who have taken any other therapy for melasma within last one month.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The modified Melasma Assessment Severity Index (mMASI) score will be the primary outcome measure.Timepoint: It will be determined at baseline before treatment and thereafter, at the end of 4, 8 and 12 weeks of treatment.
- Secondary Outcome Measures
Name Time Method Side effects related to treatment willbe recordedTimepoint: After each visit