Effects of carnitine , ubiquinone and both on the levels of serum Lp(a) and homocysteine and on the oxidative stress in heodialysis patients
Not Applicable
- Conditions
- Hemodialysis patients.Chronic renal failure
- Registration Number
- IRCT138811212779N2
- Lead Sponsor
- Vice Chancellor for Research, Tehran University of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
1. Patients under hemodialysis for at least one yer; 2. Serum levels of Lp(a) >20 mg/dl and homocysteine =>15 mg/dl; 3. Willingness to participate and filling up the consent form.
Exclusion criteria: 1. Patients with acute or chronic infection; 2. Patients taking carnitine, ubiquinone, vitamins A,E and C during the last month prior to the trial.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cardio-vascular risk factors. Timepoint: Before and after 3 months after intervention. Method of measurement: Serum levels of Lp(a) (Elisa); homocysteine (Enzymatic cycling); and malondialdehyde (spectophotometry).
- Secondary Outcome Measures
Name Time Method