EUCTR2005-003997-74-DK进行中（未招募）1 期
Depletion of regulatory T-lymphocytes by intratumoral injection of antibodies.
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Histopathologically verified cancer with metastasis. No further conventional anti-cancer treatment options.
- •Radiological visualisation of cancer/metastasis localisation must enable direct or ultrasonography mediated intratumoral injection
- •Cancer diseases preferred:
- •1. liver, primary and secondary.
- •2. mammary cancer
- •3. sarcomas
- •4. melanomas
- •5. prostate
- •6. kidney, hypernefroma
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Expected lifetime < 3 months
- •ECOG 3-4.
- •Ongoing infection
- •< 4 weeks from prior immunosuppressive therapy
- •Billirubin >2 times upper normal value
- •ASAT/ALAT >2 times upper normal value
- •abnormal creatinine
- •< 4 weeks from major surgery
- •positive pregnancy test
- •No use of safe barrier contraception
- •Steroid treatment <4 weeks from start of CT
- •Participation in other experimental treatments.
研究者
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