NCT00633607已完成不适用
Hereditary Colorectal and Associated Tumor Registry Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- Establish a Hereditary Colorectal Tumor Registry to facilitate development and implementation of epidemiological, clinical and cancer control research.
研究概览
简要总结
After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical and family histories. Data and biospecimens will be stored for potential future research projects.
研究设计
- 研究类型
- Observational
- 观察模型
- Family Based
- 时间视角
- Other
入排标准
- 年龄范围
- 8 Years 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Identified gene mutation
- •Personal history of colorectal cancer diagnosed ≤ 50
- •Personal history of cancer with tumor studies suggestive of Lynch syndrome
- •Personal history of multiple primary tumors associated with a hereditary cancer syndrome (colorectal, uterus, stomach, ovary, small bowel, hepatobiliary tract, transitional cell carcinoma of the renal pelvis/ureter, brain)
- •Personal history of one of the above cancers and a family history of one or more of the above cancers
- •Personal or family history of diffuse gastric cancer
- •From a known genetic predisposition family
- •Personal history of > 10 colon adenomas (cumulative over a lifetime)
- •Personal history of any number of hamartomatous polyps
- •Personal history of multiple large (> 1cm) serrated polyps to right of sigmoid
- •Exclusion critera:
- •Individuals under the age of 8
- •Individuals who cannot travel to Pittsburgh for in-person enrollment
- •Individuals who cannot provide informed consent
排除标准
- 未提供
结局指标
主要结局
Establish a Hereditary Colorectal Tumor Registry to facilitate development and implementation of epidemiological, clinical and cancer control research.
时间窗: 1-N/A (up to 8 years)
次要结局
未报告次要终点
研究者
Randall Brand
Principal Investigator
University of Pittsburgh
研究点 (1)
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