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Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia

Phase 1
Completed
Conditions
Intubation Complication
Interventions
Registration Number
NCT06065956
Lead Sponsor
Pakistan Navy Station Shifa Hospital
Brief Summary

Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia

Detailed Description

Comparing hemodynamic profile of patients during induction of General Anesthesia with intravenous morphine as an adjuvant drug versus Intravenous esmolol as an adjuvant agent,My aim is to study which drug has superior hemodynamic profile in terms of hemodynamic stability of patient requiring General Anesthesia.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
110
Inclusion Criteria
  • ASA 2 patients presenting for elective surgery.
Exclusion Criteria
  • Patients having major cardiac disease.
  • Metastatic disease.
  • Pregnant females.
  • Those unwilling to be part of study.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Morphine groupIntravenous morphineHalf of participants will be comprising of morphine group
Esmolol groupIntravenous morphineHalf of participants will be comprising of esmolol group
Primary Outcome Measures
NameTimeMethod
Blood pressure06 months

Change in blood pressure between baseline value and post Intubation value will be measured in millimeter of mercury (mmHg).

Pulse rate06 months

Change in pulse rate between baseline value and post intubation value will be measured per minute.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

PNS Shifa Hospital

🇵🇰

Karachi, Sind, Pakistan

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