Validation of CT Angiography and/or Magnetic Resonance Imaging markers for characterization and quantification of atherosclerosis in the carotid arteries by comparison with surgical specimens. - Carotid imaging.

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 150 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•* Patients with cerebrovascular symptoms (TIA, minor stroke) in the last six months
•* CTA of the carotid arteries (at the Erasmus Medical Center or referring centre) during the last 2
•months (CTA is performed for clinical work-up)
•* Scheduled endarterectomy of a carotid artery
•* Signed informed consent
•* At least 18 years old
•* Patients who have a documented allergy to MRI contrast media are eligible for MRI, but will not
•undergo a contrast-enhanced scan. Patients with a renal clearance (eGFR) <30 ml/minute are
•eligible for MRI, but will not undergo contrast-enhanced MRI.

•* Woman who are pregnant or lactating
•* Patients who are hemodynamically unstable
•* Having any physical or mental status that interferes with the informed consent procedure
•* Not being able to remain lying down for at least 40-45 min (e.g. patients with unstable angina, dyspnea at rest, severe pain at rest, severe back pain)
•* Contraindications for MRI (e.g. claustrophobia)
•* Metal chip in the ocular bulb identified on X-ray (If a patient affirms to ever have had a metal chip in his eyeball an X-ray will be made to check if it is still present)

发起方