Validation of CT Angiography and/or Magnetic Resonance Imaging markers for characterization and quantification of atherosclerosis in the carotid arteries by comparison with surgical specimens. - Carotid imaging.

Erasmus MC, Universitair Medisch Centrum Rotterdam0 sites150 target enrollmentStarted: TBDLast updated: April 15, 2024

Overview

No summary available.

•\* Patients with cerebrovascular symptoms (TIA, minor stroke) in the last six months
•\* CTA of the carotid arteries (at the Erasmus Medical Center or referring centre) during the last 2
•months (CTA is performed for clinical work\-up)
•\* Scheduled endarterectomy of a carotid artery
•\* Signed informed consent
•\* At least 18 years old
•\* Patients who have a documented allergy to MRI contrast media are eligible for MRI, but will not
•undergo a contrast\-enhanced scan. Patients with a renal clearance (eGFR) \<30 ml/minute are
•eligible for MRI, but will not undergo contrast\-enhanced MRI.

•\* Woman who are pregnant or lactating
•\* Patients who are hemodynamically unstable
•\* Having any physical or mental status that interferes with the informed consent procedure
•\* Not being able to remain lying down for at least 40\-45 min (e.g. patients with unstable angina, dyspnea at rest, severe pain at rest, severe back pain)
•\* Contraindications for MRI (e.g. claustrophobia)
•\* Metal chip in the ocular bulb identified on X\-ray (If a patient affirms to ever have had a metal chip in his eyeball an X\-ray will be made to check if it is still present)

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