Metabolomics and transcriptomics study in coronary artery bypass graft

Recruiting

• Conditions: Coronary artery disease patient; coronary artery disease, coronary artery bypass graft, metabolomics study, transcriptomics study

• Registration Number: TCTR20221216001
• Lead Sponsor: Faculty of medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-16
• Last Update Posted: 19 August 2024
• Study Completion: 2024-08-22

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Coronary artery disease patients that indicated for CABG surgery
2. Can perform informed consent patient
3. Age more than 18 years

Exclusion Criteria

1. Requiring concomitant procedure
2. Emergency surgery
3. all types of atrial fibrillation
4. Recent myocardial infarction not more than 2 weeks
5. Other underlying diseases including neurologic disorders, chronic renal failure requiring dialysis, liver disease, active cancer, or any other serious medical condition.
6. Absence of written informed consent
7. Recent infection (fever 38.0 C, c-reactive protein (CRP) more than 20 mg/L,)
8. Immune compromise including Anti-HIV, Hepatitis B or Hepatitis C infection, Treponema pallidum
9. Pregnant or breastfeeding

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
metabolomics profile day 3 after surgery level of metabolite

Secondary Outcome Measures

Name	Time	Method
transcriptomics profile day 3 after surgery RNA sequencing