Effect of Resistant Starch (Type-4) on Metabolic Syndrome
- Conditions
- Metabolic Syndrome
- Registration Number
- NCT01887964
- Lead Sponsor
- South Dakota State University
- Brief Summary
Metabolic syndrome is a condition characterized by excess body weight, large waist circumference, high cholesterol and glucose in the blood, and hypertension. People with metabolic syndrome are at increased risk for heart diseases. Research shows benefits of regular fiber intake in metabolic syndrome. However, due to altered taste and texture of the high fiber foods, long term intake of fiber is a challenge for metabolic syndrome patients. This study is designed to find if blinded-substitution of regular wheat flour in domestic kitchen with wheat flour enriched by an adaptable type of fiber (resistant starch-4), minimizes metabolic syndrome symptoms. this special type of fiber is also obtained from wheat.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 86
- Any individual aged 18-80 years
- Pregnant
- Lactating
- Requires special diets or dietary regimens
- On long term antibiotic therapy
- Diagnosed with gastrointestinal diseases (Irritable Bowel syndrome, Crohn's disease or Colitis)
- Immune compromised
- Have cancer
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Changes in metabolic syndrome risk components 26 weeks
- Secondary Outcome Measures
Name Time Method Changes in blood glucose indices 26 weeks fasting blood glucose, postprandial blood glucose and Hemoglobin-A1C
Changes in anthropometric outcomes 26 weeks Body weight, body mass index, systolic and diastolic blood pressure, fat mass and fat-free mass
Changes in blood lipid profile 26 weeks total cholesterol, LDL cholesterol, HDL cholesterol, non-HDL cholesterol and triglycerides
Trial Locations
- Locations (1)
South Dakota State University
🇺🇸Brookings, South Dakota, United States
South Dakota State University🇺🇸Brookings, South Dakota, United States