To find out effect and safety of polyethylene glycol and sodium hyaluronate in patient with dry eye disease
Not Applicable
Completed
- Conditions
- Health Condition 1: H048- Other disorders of lacrimal system
- Registration Number
- CTRI/2023/02/049510
- Lead Sponsor
- Pt BD Sharma PGIMS Rohtak
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Patients of either gender > 18 years of age.
Patients diagnosed with moderate dry eye disease (score 9-13) according to Khurana’scoring system.
Patients willing to give written informed consent.
Exclusion Criteria
Any structural
abnormalities
Pregnant and lactating
women.
Hypertension
Glaucoma.
Diabetes.
History of allergy to
study medication.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Schirmer-1 test <br/ ><br>2. Tear break-up time (in seconds) <br/ ><br>3. Rose Bengal staining score <br/ ><br>4. Goblet cellconjunctivalimpression cytologyTimepoint: Safety assessment will be carried out for all the treatment groups at 2 and 6 weeks
- Secondary Outcome Measures
Name Time Method 1. Fluorescein staining <br/ ><br>2. Lissamine green staining <br/ ><br>3. Likert scale using standardized facial expressionTimepoint: Safety assessment will be carried out for all the treatment groups at 2 and 6 weeks