Comparison of fentanyl vs lignocaine as pretreatment for prevention of pain on propofol injection in patients undergoing general anaesthesia
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To evaluate pain on injection of fentanyl and lignocaine pre-treatment for pain caused by propofol injection using 4 point pain score
研究概览
简要总结
Propofol is the most widely used intravenous (IV) anaesthetic agent for induction and maintenance of anaesthesia as well as for sedation inside and outside operation theatre. Propofol is almost an ideal IV anaesthetic agent, but pain on its injection is a problem. Several methods have been used to attenuate the pain. Lignocaine is used routinely. Fentanyl is also an effective alternative.
In present study, we propose to evaluate and compare fentanyl100mcg (2ml) vs lignocaine2% 40 mg (2ml)as pre-treatmentfor attenuation of pain caused by propofol injection.The patients will be observed for incidence of pain, severity of pain using four point pain score, skin reactions, haemodynamic changes and patient satisfaction score.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged between 18-60 years of either gender, giving valid informed and written consent.
- •Patients belonging to American Society of Anesthesiology(ASA) grade I, and II.
排除标准
- •Participants with a history of allergy to any of the study drugs.
- •Hemodynamically unstable participants.
- •Patients taking analgesics before surgery Participants with difficult venous cannulation with 18G IV cannula satisfactorily in any large peripheral vein of the hand.
- •Pregnant women.
结局指标
主要结局
To evaluate pain on injection of fentanyl and lignocaine pre-treatment for pain caused by propofol injection using 4 point pain score
时间窗: After 10 seconds
次要结局
- To study pain, edema, wheal and flare of patients who received fentanyl and lignocaine pre-treatment for pain caused by propofol injection.(After one hour of induction.)
- To study patient satisfaction score of patients who received fentanyl and lignocaine pre-treatment for pain caused by propofol injection.(After extubation)
研究者
Mehak Grover
Guru Gobind Singh Medical College Hospital