CTRI/2025/07/091339尚未招募2 期
To evaluate the dose and time requirement of Propofol medium chain triglygeride- long chain triglyceride (MCT - LCT) with co-administartion of nitrous oxide (N2O) during induction of general anesthesia in Ear, Nose and Throat (ENT) surgeries
JNMC1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年8月7日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the efficacy and safety of induction dose of propofol when N2O is been concurrently administered
研究概览
简要总结
The purpose of study is to evaluate Anesthetic Dose and Duration Using Propofol MCT/LCT with Nitrous Oxide in ENT Procedures.
The co-administration of N2O in fresh gas flow during induction of anesthesia is expected to reduce the induction dose and time of propofol MCT-LCT
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA one and two undergoing surgeries requiring general anesthesia for elective nose and throat surgeries with controlled ventilation weight forty to eighty kg no comorbidities.
排除标准
- •body mass index more than thirty five renal insufficiency liver dysfunction patient with anticipated difficult airway cardiorespiratory abnormalities pregnant,breast feeding female history of sleep apnoea middle ear surgery emergency surgery in neck and oral cavity patient receiving other form of analgesia undergoing surgical operations with significant hemodynamic changes.
结局指标
主要结局
To assess the efficacy and safety of induction dose of propofol when N2O is been concurrently administered
时间窗: 2-5 minutes
次要结局
- To assess the hemodynamic variations to therapeutic dose of propofol and any adverse effects during the induction process(6 minutes)
研究者
Nikita Sareen
Datta Meghe Institute of Medical Science and Research
研究点 (1)
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