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临床试验/NCT04536324
NCT04536324已完成不适用

The Absorption Rate of Subcutaneous Infused Fluid in Both Acutely Ill and Healthy Older Adults

Aalborg University Hospital1 个研究点 分布在 1 个国家目标入组 6 人开始时间: 2020年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
6
试验地点
1
主要终点
The difference in the absorption rate between acutely ill and not acutely ill.

研究概览

简要总结

The purpose of the study is to examine the rate of absorption of subcutaneous infused fluid in older adults when acutely ill compared to when they are not acutely ill.

详细描述

Dehydration is a common condition in older adults. When oral hydration is insufficient there is a need for parenteral hydration. Subcutaneous infused fluid or hypodermoclysis is a method for parenteral hydration. This method is used to treat older adults with mild to moderate dehydration or at risk of dehydration. Despite that, this method is used in older adults who are acutely ill we have a very limited understanding of the absorption time and thereby when the infused fluid is available in the circulatory system. This study aims to compare the absorption time in older adults who are acutely ill with when they are not acutely ill. Furthermore, this study aims to describe how fast the subcutaneous infused fluid is absorbed from the subcutaneous space and subsequently when it is available in the circulatory system where it has its effect.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
75 Years 至 120 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ability to give informed consent
  • Hospitalized for an acute illness

排除标准

  • Severe limitation on fluids
  • Risk of acute deterioration of illness
  • Requiring constant care
  • Short life expectancy

结局指标

主要结局

The difference in the absorption rate between acutely ill and not acutely ill.

时间窗: 8 weeks after discharge

We will compare the absorptions rate of subcutaneous infused fluid when the patients are acutely ill (during admission) and when they are not acutely ill (8 weeks after discharge).

次要结局

  • The absorption rate of subcutaneous infused fluid by count over the infusion site(We will count the activity from the start of infusions until 2 hours after all of the 250 ml have been infused.)
  • The correlation between s-albumin and absorption time.(We will count the activity from the start of infusions until 2 hours after all of the 250 ml have been infused.)
  • The absorption rate of subcutaneous infused fluid by count in the thyroid or by count in blood samples.(We will count the activity from the start of infusions until 2 hours after all of the 250 ml have been infused.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mathias Aalkjær Brix Danielsen

MD

Aalborg University Hospital

研究点 (1)

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