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临床试验/ACTRN12614000727640
ACTRN12614000727640招募中2 期

Haemodynamic effects of Milrinone in patients with heart failure and preserved ejection fraction (HFPEF)

Alfred Health0 个研究点目标入组 14 人开始时间: 2014年7月8日最近更新:
适应症

试验速览

阶段
2 期
状态
招募中
发起方
Alfred Health
入组人数
14

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Treatment
盲法
Blinded (masking used)

入排标准

年龄范围
18 Years 至 o limit(—)
性别
All

入选标准

  • Adults greater than or equal to 18 years of age, AND
  • Symptoms of HF (NYHA II-III) AND
  • Normal ejection fraction (LVEF equal to and more than 45%) with evidence of diastolic dysfunction as prescribed by ESC Working Group 15 (resting PCWP more than 12; E/e’ more than 15 or Eand e prime more than 8 and
  • and NT-BNP more than 220)

排除标准

  • Other cause for dyspnoea including moderate or severe valvular HD and pulmonary hypertension with PVR more than 4 Wood Units
  • Body mass index (BMI) more than 35 kg/m2
  • History of stress-induced syncope or ventricular tachycardia during exercise
  • Unstable coronary artery disease
  • Symptoms and signs of congestive heart failure at rest (NYHA IV)
  • Unable to perform exercise test

研究者

发起方
Alfred Health

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