Comparison of the effect of milrinone and dobutamine on pulmonary hypertensio
Phase 3
Completed
- Conditions
- Pulmonary hypertension.Other secondary pulmonary hypertensionI27.2
- Registration Number
- IRCT20211102052941N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
Patients who are candidate for heart valve transplantation and suffering pulmonary hypertension (right ventricular systolic pressure =50mmHg or meanPAP =40 mmHg or systolic PAP is mor than 50% of systemic systolic pressure)
The age over 18 years old
The consent of patient to being involved
Exclusion Criteria
Renal and hepatic failure
Emergent surgery
Necessity to inotropic drugs before surgery
Long QT interval patients
Drug allergy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulmonary blood pressure in millimeters of mercury. Timepoint: After induction of anesthesia, before CPB, after CPB, the ICU arrival moment and every 6 hours till 24 hours in ICU. Method of measurement: Pulmonary artery catheter.;Ejection fraction. Timepoint: Before surgery and 3 days after surgery. Method of measurement: Echocardiography.
- Secondary Outcome Measures
Name Time Method