High-intensity Interval Training in Patients With COPD: a Fidelity and Tolerability Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Exercise tolerability: Subjective rating of the exercise session
研究概览
简要总结
Although high-intensity training (HIIT) is widely used in the rehabilitation of patients with chronic obstructive pulmonary disease (COPD), the optimal duration of intervals in terms of patient tolerability and fidelity is unknown.Thus, we will examine the fidelity and tolerability of the two most commonly used HIIT protocols, the classical so-called 4x4min vs. 10x1min in patients with moderate to severe COPD.
详细描述
12 patients with severe to moderate COPD will be included in the study, where two different HIIT interventions will be compared with regards to fidelity and tolerability. Baseline measurements will be performed to assess fitness and cardiopulmonary health status for the included patients. The baseline measurements include a medical health interview and examination (blood pressure, heart rate, ECG), a maximal oxygen consumption (VO2max) test, lung function testing (dynamic spirometry, whole body plethysmography, diffusing capacity), and an assessment of body composition. The following two visits consist of two different HIIT protocols.
Each training session is evaluated by Borg Scale (5) and the Likert Scale (6), as well as time spent in with a heart rate above 85% of maximum. Each HIIT session is separated by at least a 3-day wash-out period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women
- •18-80 years
- •Moderate to severe COPD(GOLD stage II to III)
排除标准
- •Known ischaemic heart disease
- •Known heart failure
- •Previous or current coronavirus disease 2019 (COVID-19)
- •Dementia or other severe neurological disease
- •Known vascular
- •Symptoms of disease within 2 weeks prior to the study
- •Pregnancy
结局指标
主要结局
Exercise tolerability: Subjective rating of the exercise session
时间窗: 1 week
Tolerability is measured with a 10-point Likert scale, where the participants evaluate the two HIIT protocols. They will anser two quesitens: 1. How tolerable was todays traning? 2. How much did you enjoy todays training? Where 1 means not at all, and 10 means alot. The Likert scale is scored as: Red: 1-2 Amber: 3-4 Green: +5
Exercise feasibility: Relative dose intensity (RDI) of exercise
时间窗: 1 week
RDI (%) of exercise, defined as prescribed exercise dose / performed exercise dose x 100 Evaluated with a Red-Amber-Green system: * Green: If ≥85% of the training is completed * Amber: If 50-85% of the training is completed * Red: If ≤ 50% of the training is completed
Exercise feasibility: Exercise sessions attendance rate
时间窗: 1 week
Exercise sessions attendance rate (%), defined as number of attended exercise sessions / number of prescribed exercise sessions x 100
Exercise feasibility: Exercise sessions requiring dose modifications
时间窗: 1 week
Incidence of exercise sessions requiring dose modifications, defined as any deviation from the prescribed exercise.
次要结局
未报告次要终点
研究者
Ronan Berg
MD, DMSc, Associate professor
Rigshospitalet, Denmark