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临床试验/NCT03221829
NCT03221829Unknown不适用

A Retrospective Analysis of Spinal Anaesthesia for Transurethral Resection of Bladder Tumour in Elderly Patients: A Single Centre Experience From 2007 to 2017

Medical University of Warsaw1 个研究点 分布在 1 个国家目标入组 2,800 人开始时间: 2017年7月6日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
2,800
试验地点
1
主要终点
The effectiveness of spinal anaesthesia for TURBT evaluated by a number of participants that had the procedure done, without the need of conversion to general anaesthesia .

研究概览

简要总结

The aim of the study was to evaluate the safety and effectiveness of spinal anesthesia among elderly patients The basic methods for diagnosis and management of bladder cancer include endoscopic procedures (cystoscopy, trans-urethral resection of bladder tumour TURBT). The age of most patients is above 60, which increases the risk of complications during the perioperative period. Usually the leading anaesthesia method in TURBT procedures is regional, mainly spinal, anaesthesia. Although the prevalence of regional upon general anaesthesia is questioned, certain positive aspects of regional anaesthesia are indisputable. Maintaining logical communication with a patient during the procedure enables early diagnosis of complications (TUR syndrome, bladder perforation). Undeniably, regional anaesthesia ensures the best pain management in the early post-operative period. The simplicity of performing an efficacious spinal block and its cost-effectiveness are additional factors, which have contributed to the acknowledgement of the method as the standard of anaesthesia for transurethral procedures.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • TURBT procedure
  • spinal anaesthesia
  • age over 60

排除标准

  • general anaesthesia

结局指标

主要结局

The effectiveness of spinal anaesthesia for TURBT evaluated by a number of participants that had the procedure done, without the need of conversion to general anaesthesia .

时间窗: 6 months

The investigator evaluates whether the procedure could be completely performed under spinal anesthesia

次要结局

  • The influence of the bupivacaine spinal dose on bradycardia evaluated by a heart rate measurements(6 months)
  • The influence of the bupivacaine dose on hypotension evaluated by the non-invasive blood pressure measurements(6 months)
  • Experienced and non-experienced anesthetist does it influence the spinal anaesthesia success(6 months)
  • Experienced and non-experienced anesthetist does it influence the bupivacaine dose(6 months)

研究者

发起方
Medical University of Warsaw
申办方类型
Other
责任方
Principal Investigator
主要研究者

Karolina Dobrońska

MD. PhD.

Medical University of Warsaw

研究点 (1)

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