Optimizing diagnosis of abdominal vein thrombosis with MRI- the Rhea study
- Conditions
- - non-symptomatic chronic (incidental) splanchnic vein thrombosis (SVT)- acute splanchnic vein thrombosis (SVT)- portal vein thrombosis (PVT)- mesenteric vein thrombosis (MVT)- splenic vein thrombosis (SpVT) - Budd-Chiairi syndrome (BCS)Nederlands:- asymptomatische chronische (incidentele) buivene trombose - acute buikvene trombose- poortader trombose - mesenteriale vene trombose - Milt vene trombose- Budd-Chiairi syndroom (BCS)
- Registration Number
- NL-OMON21809
- Lead Sponsor
- MC (Leids Universitair Medisch Centrum)
- Brief Summary
none
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 73
Patients with confirmed acute SVT; definitions provided in paragraph 4.2 (Cases, group 1)
- Patients with confirmed non-symptomatic chronic SVT, defined by incident SVT treated for at least 3 months and with chronic thrombi on 2 serial imaging tests with at least 3 months interval (controls, group 2)
- MRI contra-indication (including but not limited to a cardiac pacemaker or subcutaneous defibrillator; vascular clips in the cerebral vessels; metal splinter in the eye, a hearing aid that cannot be removed; a neurostimulator that cannot be removed; a hydrocephalus pump)
- A medical condition, associated illness or co-morbid circumstances that precludes completion of the study procedures (MRI and 90-day follow-up assessment), including but not limited to life-expectancy less than 3 months, inability to lie flat, morbid obesity preventing use of MR and claustrophobia.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To explore the diagnostic accuracy of MRDTI in the diagnostic management of acute and chronic SVT in a prospective diagnostic proof of concept study
- Secondary Outcome Measures
Name Time Method 1) To optimise MRDTI sequences for imaging SVT. <br /><br>2) To assess the interobserver agreement of the readers of MRDTI for suspected SVT. <br>