ISRCTN98001632已完成不适用
on-invasive assessment of haemodynamic response to beta-blockers using magnetic resonance imaging in patients with portal hypertension
niversity of Edinburgh/ACCORD0 个研究点目标入组 20 人开始时间: 2017年5月19日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Male or female patients aged 18-80 with liver cirrhosis
- •2. Portal hypertension in whom commencement of beta-blockers is clinically indicated
排除标准
- •1. Contraindication to Beta-Blocker therapy (such as moderate to severe asthma)
- •2. Contraindication to MRI scan
- •3. Contraindication to administration of gadolinium-based MRI contrast (including eGFR <30mL/min)
- •4. Concomitant use of other vasoactive drugs (e.g. nitrates, phosphodiesterase inhibitors)
- •5. Previous TIPSS insertion
- •6. Portal vein thrombosis
- •7. Hepatocellular carcinoma
- •8. Pregnancy or breastfeeding
- •9. Inability to obtain informed consent (e.g. refusal/overt hepatic encephalopathy)
研究者
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