Haemodynamic response to intubatio
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/05/052837
- Lead Sponsor
- M REETHM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients undergoing elective surgery under general anesthesia and with valid consent
2.ASA grade 1 and 2 patients
Exclusion Criteria
1.Emergency surgeries
2.Prior sensitization or allergic reaction to propofol, ketamine, soy or egg products
hemodynamic instability
3.Head injury
4.Increased intracranial or intraocular pressure
5.Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Haemodynamic stability in terms of systolic blood pressure, diastolic blood pressure and mean arterial pressure are maintained when patient is induced with ketofol (combination of propofol and ketamine ) rather than when used alone as an induction agentsTimepoint: Baseline , 1 minute ,3minutes , 5 minutes ,15 minutes after intubation
- Secondary Outcome Measures
Name Time Method Decrease in post operative nausea and vomiting and decreased incidence of hallucinationsTimepoint: Immediately after extubation, 15 minutes , 30 minutes and 1 hour after extubation