The effects of transcranial magnetic stimulation on eating behaviors and body weight in obese patient with depressio
- Conditions
- Mental and behavioral disorders
- Registration Number
- KCT0005492
- Lead Sponsor
- The Catholic University of Korea, St. Vincent's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
19 to 70 years old
- BMI = 25kg/m2
- Diagnosis and Statistics Handbook for Mental Disorders-Patients diagnosed as depressive disorder according to the 5th edition (DSM-V) diagnostic criteria and showing moderate symptoms (BDI 14~28 points)
- Patients taking 2 or less antidepressants at a stable dose for the last 4 weeks
• Past history of head or eye injury or epilepsy
• Body metallic implants, pacemaker, claustrophobia and any other contraindication to fMRI or rTMS;
• Current use of psychotropic drugs (except for antidepressants on a stable dose for at least one month)
• Current use of any anti-obesity drug (three months washout period for any other medication)
• Pregnancy or breast feeding
• Past history of Diabetes Mellitus, thyroid disease, renal disease and malignancy
• Major psychiatric disorder requiring immediate treatment
• Substance dependence
• Individuals currently receiving any psychological therapy for their eating disorder
• Substance dependence
• severe infection, metabollic acidosis, acromegaly adn Cushing syndrome
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in Body Weight
- Secondary Outcome Measures
Name Time Method Korean eating attitude test (KEAT-26) scores;visceral fat assessed by CT;structural and functionl change assessed by brain MRI;CERAD-K score;Beck Depression Inventory score;dopamine, serotonin, cortisol