Preoperative Nutritional Status and Postoperative Acute Kidney Injury
- Conditions
- Postoperative Acute Kidney Injury
- Registration Number
- NCT05945940
- Lead Sponsor
- Rao Sun
- Brief Summary
There is a high prevalence of postoperative acute kidney injury (AKI) in patients who undergo intra-abdominal surgery, and it is particularly common in the elderly. Identifying high-risk patients for postoperative AKI early can facilitate the development of preventive and therapeutic management strategies.
The goal of this retrospective study is to investigate the predictive value of preoperative nutritional status, as measured by three scoring systems - the geriatric nutritional risk index (GNRI), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score - on postoperative AKI in elderly patients undergoing major abdominal surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2977
- aged ≥ 65 years
- intra-abdominal procedures including gastric, colorectal, pancreatic, prostate, and urinary bladder surgeries, as well as abdominal exploration.
- surgery duration lasting longer than 2 hours.
- patients with an American Society of Anesthesiologists (ASA) physical status V.
- those with concurrent cardiac or renal surgeries.
- those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis).
- those did not have sufficient data required for nutritional evaluation or AKI evaluation.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative acute kidney injury Within 7 days after surgery In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Rao Sun
🇨🇳Wuhan, China