Effects of Infrared-LED Illumination Applied During Treadmill Training in Postmenopausal Women
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Effects of Infrared-LED Illumination Associated with Treadmill Training
研究概览
简要总结
The investigators hypothesis is that the infrared-LED illumination during treadmill training can enhance physical performance in postmenopausal women. The basis for such a hypothesis is based on the fact that the light therapy during the intense metabolic stage caused by exercise may be more efficient.
详细描述
Phototherapy improves cellular activation via absorption of photons by chromophores present in the protein components of the mitochondrial respiratory chain - mainly NADH dehydrogenases and cytochrome C oxidase, which leads to increased electron transport, production of ATP, and tissue regeneration (skin, muscle, bone, and nerves). Moreover, phototherapy stimulates the anti-inflammatory effect with analgesia and vasodilatation. Regarding body aesthetics, phototherapy increases microcirculation, lymphatic drainage, as well as collagen synthesis for the treatment of cellulite. The objective of this study was to develop and evaluate the effects of a new clinical procedure: infrared radiation originated from LEDs associated with treadmill training in postmenopausal women. LED arrays were developed for an irradiation of a large area, such as hip and quadriceps muscles, main actuators during stance and swing phases. These body parts are furthermore areas where there is incidence of osteoporosis, mainly at the femur, localized fat deposits, and cellulite. Infrared radiation (850 nm) was selected because this spectral range shows better skin penetration compared to red interval.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 60 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Postmenopausal women
- •Caucasian
- •50 and 60 years of age
排除标准
- •Neurological disease
- •Inflammatory disease
- •Pulmonary disease
- •Oncological disease
- •Cardiac disease
- •Endocrinopathy
- •Musculotendinous or articular injuries
- •Hormone replacement therapy or osteoporosis drugs
- •Cigarette smoking
结局指标
主要结局
Effects of Infrared-LED Illumination Associated with Treadmill Training
时间窗: 12 months
Quantitative and qualitative evaluations
次要结局
- Thermography(Baseline)
- Maximal exercise testing(Baseline and 6 months)
- Isokinetic concentric exercise testing(Baseline, 6 months and 12 months)
- Biochemical tests(Baseline and 6 months)
- Quality of life(Baseline and 6 months)
- Dietary habits(Baseline and 6 months)
- Exercise tolerance and heart rate variability(Baseline and 6 months)
- Bone mineral density(Baseline and 12 months)
研究者
Fernanda Rossi Paolillo
Ph.D
University of Sao Paulo
