Infrared-LED During Physical Training for Rehabilitation, Physical Performance and Body Aesthetics
- Conditions
- Healthy
- Interventions
- Device: Photon stimulation by light-emitting diodes (LEDs)Other: Treadmill training
- Registration Number
- NCT01610232
- Lead Sponsor
- University of Sao Paulo
- Brief Summary
The investigators hypothesis is that the infrared-LED illumination during treadmill training can enhance physical performance in postmenopausal women. The basis for such a hypothesis is based on the fact that the light therapy during the intense metabolic stage caused by exercise may be more efficient.
- Detailed Description
Phototherapy improves cellular activation via absorption of photons by chromophores present in the protein components of the mitochondrial respiratory chain - mainly NADH dehydrogenases and cytochrome C oxidase, which leads to increased electron transport, production of ATP, and tissue regeneration (skin, muscle, bone, and nerves). Moreover, phototherapy stimulates the anti-inflammatory effect with analgesia and vasodilatation. Regarding body aesthetics, phototherapy increases microcirculation, lymphatic drainage, as well as collagen synthesis for the treatment of cellulite. The objective of this study was to develop and evaluate the effects of a new clinical procedure: infrared radiation originated from LEDs associated with treadmill training in postmenopausal women. LED arrays were developed for an irradiation of a large area, such as hip and quadriceps muscles, main actuators during stance and swing phases. These body parts are furthermore areas where there is incidence of osteoporosis, mainly at the femur, localized fat deposits, and cellulite. Infrared radiation (850 nm) was selected because this spectral range shows better skin penetration compared to red interval.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 45
- Postmenopausal women
- Caucasian
- 50 and 60 years of age
- Healthy
- Neurological disease
- Inflammatory disease
- Pulmonary disease
- Oncological disease
- Cardiac disease
- Endocrinopathy
- Musculotendinous or articular injuries
- Hormone replacement therapy or osteoporosis drugs
- Cigarette smoking
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description LED Group Photon stimulation by light-emitting diodes (LEDs) Phototherapy associated with treadmill training Exercise Group Treadmill training Treadmill training
- Primary Outcome Measures
Name Time Method Effects of Infrared-LED Illumination Associated with Treadmill Training 12 months Quantitative and qualitative evaluations
- Secondary Outcome Measures
Name Time Method Thermography Baseline Cutaneous temperature measurements
Maximal exercise testing Baseline and 6 months Progressive aerobic exercise testing on treadmill (Modified Bruce Protocol)
Isokinetic concentric exercise testing Baseline, 6 months and 12 months Peak torque, power, work, and fatigue of the dominant quadriceps were measured using the isokinetic dynamometer
Biochemical tests Baseline and 6 months Thyroid stimulating hormone (TSH), urea, creatinine, triglycerides, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very low-density lipoprotein (VLDL) cholesterol, insulin and glucose
Quality of life Baseline and 6 months Menopause Rating Scale (MRS) and Women´s Health Questionnaire (WHQ)
Dietary habits Baseline and 6 months 3-day dietary record
Exercise tolerance and heart rate variability Baseline and 6 months Submaximal constant-speed testing and heart rate variability via autonomic reflex testing
Bone mineral density Baseline and 12 months Bone mineral density (femoral neck, wrist, and lumbar spine) via dual-energy x-ray absorptiometry (DXA)
Trial Locations
- Locations (1)
Optics Group from Physics Institute of São Carlos (IFSC), University of São Paulo (USP)
🇧🇷São Carlos, São Paulo, Brazil