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临床试验/NCT01610232
NCT01610232已完成1 期

Effects of Infrared-LED Illumination Applied During Treadmill Training in Postmenopausal Women

University of Sao Paulo2 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2009年12月最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
入组人数
45
试验地点
2
主要终点
Effects of Infrared-LED Illumination Associated with Treadmill Training

研究概览

简要总结

The investigators hypothesis is that the infrared-LED illumination during treadmill training can enhance physical performance in postmenopausal women. The basis for such a hypothesis is based on the fact that the light therapy during the intense metabolic stage caused by exercise may be more efficient.

详细描述

Phototherapy improves cellular activation via absorption of photons by chromophores present in the protein components of the mitochondrial respiratory chain - mainly NADH dehydrogenases and cytochrome C oxidase, which leads to increased electron transport, production of ATP, and tissue regeneration (skin, muscle, bone, and nerves). Moreover, phototherapy stimulates the anti-inflammatory effect with analgesia and vasodilatation. Regarding body aesthetics, phototherapy increases microcirculation, lymphatic drainage, as well as collagen synthesis for the treatment of cellulite. The objective of this study was to develop and evaluate the effects of a new clinical procedure: infrared radiation originated from LEDs associated with treadmill training in postmenopausal women. LED arrays were developed for an irradiation of a large area, such as hip and quadriceps muscles, main actuators during stance and swing phases. These body parts are furthermore areas where there is incidence of osteoporosis, mainly at the femur, localized fat deposits, and cellulite. Infrared radiation (850 nm) was selected because this spectral range shows better skin penetration compared to red interval.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
None

入排标准

年龄范围
50 Years 至 60 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Postmenopausal women
  • Caucasian
  • 50 and 60 years of age

排除标准

  • Neurological disease
  • Inflammatory disease
  • Pulmonary disease
  • Oncological disease
  • Cardiac disease
  • Endocrinopathy
  • Musculotendinous or articular injuries
  • Hormone replacement therapy or osteoporosis drugs
  • Cigarette smoking

结局指标

主要结局

Effects of Infrared-LED Illumination Associated with Treadmill Training

时间窗: 12 months

Quantitative and qualitative evaluations

次要结局

  • Thermography(Baseline)
  • Maximal exercise testing(Baseline and 6 months)
  • Isokinetic concentric exercise testing(Baseline, 6 months and 12 months)
  • Biochemical tests(Baseline and 6 months)
  • Quality of life(Baseline and 6 months)
  • Dietary habits(Baseline and 6 months)
  • Exercise tolerance and heart rate variability(Baseline and 6 months)
  • Bone mineral density(Baseline and 12 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fernanda Rossi Paolillo

Ph.D

University of Sao Paulo

研究点 (2)

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