The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms
Phase 2
Completed
- Conditions
- Gingivitis
- Interventions
- Registration Number
- NCT00972803
- Lead Sponsor
- Tabriz University
- Brief Summary
Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth. The purpose of this study was to evaluate the effects of pistacia Mutica (PM) mouth wash on de novo dental plaque plaque formation, gingival inflammation indices and oral microorganisms.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- had merely gingivitis (pocket depth≤3 mm, no attachment loss)
- without any fixed or removable oral appliances
Exclusion Criteria
- Individuals who had a history of any relevant systemic diseases
- Individuals who had a history of any drug usage
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description pistacia Mutica pistacia Mutica extract The subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days. placebo Placebo The subjects were asked to use a mouthwash containing Placebo twice a day for 4 days. Chlorhexidine Chlorhexidine The subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days.
- Primary Outcome Measures
Name Time Method The effects of pistacia Mutica extract (PM) on de novo plaque formation. In a 4 days experimental periods followed by a 10 days wash-out periods.
- Secondary Outcome Measures
Name Time Method staining effects of pistacia Mutica extract in comparison to placebo or Chlorhexidine In a 4 days experimental periods followed by a 10 days wash-out periods
Trial Locations
- Locations (1)
Drug Applied Science Center, tabriz Univ. of Medical Sciences
🇮🇷Tabriz, East azarbaijan, Iran, Islamic Republic of