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The Influence of Sensory Phenotype on the Risk of Developing Neuropathic Pain

Conditions
Peripheral Nerve Injury
Polyneuropathy
Neuropathic Pain
Interventions
Other: QST, Questionnaires
Registration Number
NCT02666456
Lead Sponsor
University of Kiel
Brief Summary

Cross-sectional and longitudinal analysis of the somatosensory phenotype, assessed by quantitative sensory testing (QST) and Information obtained by questionnaires to detect risk factors for neuropathic pain development and chronification in painless and chronic pain patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
1500
Inclusion Criteria
  • Chronic peripheral neuropathic pain or
  • Painless Patient with risk to develop neuropathic pain (post-surgery, chemotherapy-induced)
Exclusion Criteria
  • Minors

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Cross-sectional cohortQST, QuestionnairesPatients with chronic peripheral neuropathic pain
Longitudinal cohortQST, QuestionnairesPainless patients before and after potential chronic neuropathic pain-inducing interventions (chemotherapy, Operation)
Primary Outcome Measures
NameTimeMethod
Somatosensory phenotype detected by quantitative sensory testing (QST)Single assessment at baseline (cross-sectional study). Report of complete cohort data at study completion

The somatosensory phenotype will be assessed by quantitative sensory testing (QST) once at baseline

Change of neuropathic pain: Development and chronification of neuropathic pain detected by DN4 questionnaireAssessment of change of neuropathic pain from baseline and 6 months after study enrollment (longitudinal study). Report of complete cohort data at study completion.

Assessment with DN4 pain questionnaire

Secondary Outcome Measures
NameTimeMethod
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