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Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

Recruiting
Conditions
Cytomegalovirus Infections
Interventions
Diagnostic Test: CMV PCR on saliva
Registration Number
NCT06522880
Lead Sponsor
University of Massachusetts, Worcester
Brief Summary

The goal of STAGE I of the CMV TransmIT Study is to determine the prevalence of CMV shedding in children up to and including 36 months of age in large group childcare centers and in staff who regularly work at the center. Participants will complete a health survey and provide one saliva sample for CMV PCR testing. In addition, infrastructure for the study will be developed (e.g. community engagement to build the network of centers, data pipelines, digital platform, sampling workflows) and participant sample collection at home will be piloted. These activities will inform the design of STAGE II.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
StaffCMV PCR on salivaAll staff members in large group childcare centers attended by children participants
ChildrenCMV PCR on salivaChildren up to and including 36 months in large group childcare centers in the study network
Primary Outcome Measures
NameTimeMethod
Prevalence of CMV sheddingStage I up to 2 years

Prevalence of CMV shedding in children and childcare center staff. Shedding measured by CMV PCR on saliva.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

UMass Chan Medical School

🇺🇸

Worcester, Massachusetts, United States

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