To evaluate macular and peripapillary microvascular changes in systemic hypertension as measured by optical coherence tomography angiography technology
Not yet recruiting
- Conditions
- Background retinopathy and retinalvascular changes,
- Registration Number
- CTRI/2022/04/041654
- Lead Sponsor
- Department of Ophthalmology
- Brief Summary
This study aims at evaluating changes occurring in the microvasculature of the retina primarily evaluated at the macular and peripapillary region through oct angiography in hypertensive patients in comparison to the normal control group. The study aims at picking up subtle signs of microvascular damage as measured by oct and octa technology well before clinical signs of hypertension manifest in the body.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
1.Hypertensive patients on medication for more than 5 years 2.Age: 30-60 years 3.BCVA ≥ 6/12.
Exclusion Criteria
- 1.Significant ocular media opacity (in order to maximize good quality images) 2.Grade 3 hypertensive retinopathy and above (according to Keith Wagener Barker classification).
- 3.Any other ocular pathology, e.g. macular edema, diabetic retinopathy, optic nerve disorders etc.
- 4.Any intraocular surgery 5.Any other systemic illness.
- 6.Refractive errors (> +3 D, axial length (AL) >26.0 mm).
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1-To measure Macular and peripapillary OCTA parameters (VD, PD and FAZ dimensions) in systemic hypertension vs control group. Baseline
- Secondary Outcome Measures
Name Time Method 1) Measurement of structural OCT Parameters (CMT, GC-IPL and RNFL thicknesses) in systemic hypertension vs normal control group.
Trial Locations
- Locations (1)
Guru Nanak Eye Centre
🇮🇳Delhi, DELHI, India
Guru Nanak Eye Centre🇮🇳Delhi, DELHI, IndiaDr Yashi GuptaPrincipal investigator9873976836yaasshi12@gmail.com