The effectiveness in land-based exercise, water-based exercise and water-based exercise plus cognitive training on cognition and functional mobility in Thai elderly with mild cognitive impairment

Phase 2

• Conditions: Mild cognitive impairment in elderly; Mild cognitive impairment, Water-based exercise, Cognition, Mobility

• Registration Number: TCTR20220718003
• Lead Sponsor: Thammasat University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-18
• Last Update Posted: 19 August 2024
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

1. Age 65 years old or above
2. Have the Montreal Cognitive Assessment (MoCA) scores between 17-24 points
3. Pass the Lawton Instrumental Activities of Daily Living Scale (L-IADL)
4. Pass Physical Activity Readiness Questionnaires Plus (PAR-Q+)
5. Living in Pathum Thani or Nakhon Pathom provinces.
6. No history of exacerbation respiratory diseases in the past 6 months
7. Able to understand, communicate and write in the Thai language.

Exclusion Criteria

1. Have problems with mental illness, uncontrol cardiovascular diseases, acute exacerbation of COPD or uncontrolled asthma diagnosed by a physician.
2. Have Problems with musculoskeletal problems that disturbed exercise and movement such as fracture
3. Have neurological disorders (e.g., stroke, epilepsy)
4. Uncontrolled the symptoms of diabetes.
5. Blood pressure >180/120 mmHg.
6. Resting heart rate > 120 beats/minutes
7. Have urinary incontinent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The Montreal Cognitive Assessment (MoCA) baseline, 4 week, 8 week, 12 week screening and assess global cognition.,The stroop color and word test (SCWT) baseline, 4 week, 8 week, 12 week assess executive function (Inhibitory control),The Trail Making Test Part A,B(TMT-A,B) baseline, 4 week, 8 week, 12 week assess executive function (mental flexibility).,The digit span test (DS) baseline, 4 week, 8 week, 12 week assess working memory.,The Timed up and go test (TUG) and The Time up and go test with dual-tasking (TUGdt-calculation) baseline, 4 week, 8 week, 12 week measure mobility, balance, and walking ability.,The 6-minutes-walk Test (6MWT) baseline, 4 week, 8 week, 12 week measure walking performance and cardiopulmonary fitness. ,The Clock Drawing Test (CDT) baseline, 4 week, 8 week, 12 week nonverbal screening tool,10 Meter walk test (10MWT) baseline, 4 week, 8 week, 12 week measure walking speed

Secondary Outcome Measures

Name	Time	Method
36-Item Short Form Survey (SF-36) baseline, 4 week, 8 week, 12 week measure quality of life,Fullerton senior fitness test baseline, 4 week, 8 week, 12 week 30-second chair stand, 2 minute step test, the arm-curl test, hand grip dynamometer, chair sit and reach test,respiratory muscle strength and Oxygen Saturation baseline, 4 week, 8 week, 12 week respiratory pressure meter and finger oximeter,Arterial stiffness baseline, 4 week, 8 week, 12 week measure arterial flexibility