Single Adductor-canal-block Versus Peri-articular Infiltration on Outcome After Total Knee Arthroplasty
- Conditions
- Osteoarthritis,Knee
- Interventions
- Drug: single adductor-canal-blockDrug: periarticular infiltration
- Registration Number
- NCT02784041
- Lead Sponsor
- Peking Union Medical College Hospital
- Brief Summary
The purpose of this study is to compare the effect of single adductor-canal-block versus single femoral nerve block on the recovery after total knee arthroplasty.
- Detailed Description
The aim of this study is to assess the effect of different analgesic effects on the outcome of patients undergoing total knee arthroplasty. Patients who will have primary unilateral total knee replacement between September 2016 to June 2018 at Peking Union Medical College Hospital and meet the inclusion criteria will be included. They are randomized into two groups. The total knee arthroplasty is performed by one surgeon and adductor-canal block is performed by one anesthesiologist who is not responsible for follow-up. Patients on both groups will have intravenous patient control analgesia with 1 mg morphine/bolus. One residency is responsible for the follow-up.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 200
- osteoarthritis
- unilateral total knee arthroplasty
- ASA grade I - II
- normal cognitive function.
- patients refuse
- BMI > 35
- diagnosis other than osteoarthritis
- allergy to the drugs used or contraindication to the intervention
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description single adductor-canal-block single adductor-canal-block Patients in this group will receive ultrasound guided single adductor-canal- block with 0.35% ropivacaine 25ml. periarticular infiltration periarticular infiltration patients in this group will receive periarticular infiltration of local anesthetic.
- Primary Outcome Measures
Name Time Method the time required for functional recovery from the date of the surgery to the time when the patients meet the criteria of functional recovery. The earliest day on which the patient achieves the criteria of functional recovery will be recorded and the average time is 7 days after surgery. Patients are evaluated postoperatively to determine whether the patients have meet the criteria of functional recovery.The criteria of functional recovery are as followings: walking distance more than 70m with crutch, getting up or standing up independently and visual analog score less than 5 both in rest and after movement. Before discharge, patients are assessed every morning. After discharge, patients are followed up by phone every two days.
- Secondary Outcome Measures
Name Time Method postoperative morphine consumption 6h, 24h, 48h after the surgery Consumptions of morphine are recorded at 6h, 24h, 48h after the surgery.
postoperative WOMAC scales pre-operative, three months,six months and one year afer the surgery We compare the WOMAC scales of two groups before, three months, six months, and one year after the surgery.
Postoperative complications daily after the surgery until discharge from hospital, expected average up to 5 days after the surgery Any complication, including nause and vomiting, deep vein thrombosis, pulmonary embolism, pulmonary infection, urinary tract infection,cardiovascular event and falls are recorded during inhospital stay.
postoperative VAS scale pre-operative, 6h postoperative, 24h postoperative, 48h postoperative, one month postoperative, three-month postoperative, one year postoperative Pain at rest and while moving are evaluated by a visual analog scale preoperative, 6h, 24h, 48h, 1month, 3 months and 1 year after the surgery.
postoperative SF-36 score pre-operative, three months,six months and one year afer the surgery We compare the SF-36 score of two groups before, three months,six months and one year after the surgery.
Trial Locations
- Locations (1)
Peking Union Medical College Hospital
🇨🇳Beijing, China