Stiffness Measurement of Liver Tumors and Visceral Parenchyma
- Conditions
- Hepatocellular Carcinoma
- Interventions
- Other: stiffness measurement using ARFI
- Registration Number
- NCT01343212
- Lead Sponsor
- China Medical University Hospital
- Brief Summary
The investigators are measuring hepatocellular carcinoma(HCC)stiffness using Acoustic Radiation Force Impulse (ARFI) technique to enhance the diagnostic accuracy for HCC stratifications and treatment efficacy.
- Detailed Description
Regression modelings as well as validity testings including cut-off identification will be acquired by performing both qualitative and quantitative measurements of HCC using reference diagnostic modalities e.g. pathology grading, dynamic CT scanning, etc.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
with HCC
Exclusion Criteria
- subjects with liver cancer other than HCC
- subjects with treated HCC
- post major abdominal surgery
- contraindications to liver tumor biopsy
- contraindications to local percutaneous treatment of liver tumors
- ARFI measurement low quality
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description newly diagnosed HCC stiffness measurement using ARFI * Subjects with newly diagnosed untreated hepatocellular carcinoma (HCC) will be enrolled. * Subjects with the following conditions will be excluded: liver cancer other than HCC, treated HCC, post major abdominal surgery, contraindications to liver tumor biopsy, contraindications to local percutaneous treatment of liver tumors, low quality ARFI measurement
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hepatogastroenterology, Department of Internal Medicine, China Medical University Hospital
🇨🇳Taichung, Taiwan