Skip to main content
MedPathMedPath Home
Clinical Trials/NCT02156661
NCT02156661
Completed
Phase 1

Oxytocin and Emotion Processing

University Hospital, Bonn0 sites97 target enrollmentMay 2013
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsHealthy Males
InterventionsOxytocin
DrugsOxytocin

Overview

Phase
Phase 1
Intervention
Oxytocin
Conditions
Healthy Males
Sponsor
University Hospital, Bonn
Enrollment
97
Primary Endpoint
Brain activity
Status
Completed
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSimilar Trials

Overview

Brief Summary

The purpose of this study is to determine whether oxytocin influences emotional processing and learning of emotional and social stimuli.

Detailed Description

An effect of OXT on emotion processing and anxiety has been broadly investigated in animal studies. However, in humans, effects seem more complex. The rationale of the study is to examine direct effects of OXT to processing and learning of emotional and social values in humans.

Registry
clinicaltrials.gov
Start Date
May 2013
End Date
June 2014
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Sponsor
University Hospital, Bonn
Responsible Party
Principal Investigator
Principal Investigator

Rene Hurlemann

Professor

University Hospital, Bonn

Eligibility Criteria

Inclusion Criteria

  • •Healthy male volunteers

Exclusion Criteria

  • •Current or past psychiatric disease
  • •Current or past physical illness
  • •Psychoactive medication
  • •Tobacco smokers
  • •MRI contraindication

Arms & Interventions

Placebo

Placebo nasal spray

Intervention: Oxytocin

Oxytocin

Oxytocin: Syntocinon-Spray, Novartis intranasal administration, 24 IU oxytocin; ; 3 puffs per nostril, each with 4 IU OXT

Intervention: Oxytocin

Outcomes

Primary Outcomes

Brain activity

Time Frame: During emotion processing

fMRI

Secondary Outcomes

  • Psychophysiological response(During stimuli presentation)

Similar Trials

Unknown
Phase 2
Effects of Oxytocin on Emotion Recognition and Response InhibitionThe Impact of Oxytocin on Social Cognition
NCT02350946RWTH Aachen University40
Completed
Phase 4
Oxytocin and Emotion RecognitionHealth
NCT01216605University Hospital Freiburg56
Completed
Not Applicable
The Effects of Oxytocin on Affective TouchHealthy
NCT03282162University of Electronic Science and Technology of China50
Completed
Phase 4
Oxytocin and Attachment-related Interpretation BiasTrust
NCT02737254Universitaire Ziekenhuizen KU Leuven100
Completed
Early Phase 1
The Neural Basis of Oxytocin's Effects on EmpathyHealthy
NCT03084029University of Electronic Science and Technology of China72