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临床试验/NCT04884061
NCT04884061进行中(未招募)不适用

Description of the Vasculature Pattern of the Bronchial Tree During Infection With SARS-CoV2 by Narrow Band Imaging Bronchoscopy

Centre Hospitalier Universitaire, Amiens1 个研究点 分布在 1 个国家目标入组 27 人开始时间: 2021年5月7日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
27
试验地点
1
主要终点
Variation of the vasculature pattern of the bronchial mucosa between the three patient groups

研究概览

简要总结

Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a submucosal network. The Narrow Band Imaging technique is used during bronchoscopy to achieve a maximum contrast of vessels and the surrounding mucosa. Therefore, it enables to observe the microvessel structure and its distribution in the bronchial mucosa. The aim of this study is to describe the vasculature pattern of the bronchial tree during infection with SARS-CoV2.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who undergo bronchoscopy with image and/or videos recording of NBI aspect of the proximal bronchial tree (carina, right and left upper lobe).
  • Patients hospitalized with SARS-CoV2 infection proven by RT-PCR test
  • patients hospitalized with lower respiratory tract infections unrelated to SARS-CoV2 (RT-PCR negative for SARS-CoV2)
  • Patients who have had bronchoscopy performed as part of the assessment of a distal pulmonary nodule (RT-PCR negative for SARS-CoV2).

排除标准

  • Patients under legal protection
  • Patients who refuses the use of his personal medical data

结局指标

主要结局

Variation of the vasculature pattern of the bronchial mucosa between the three patient groups

时间窗: 2 months

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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