The effect of Sour tea supplementation in nonalcoholic fatty liver disease.
Phase 3
- Conditions
- onalcoholic Fatty Liver Disease..Nonalcoholic steatohepatitis (NASH)K75.81
- Registration Number
- IRCT20140208016529N3
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Patients with the nonalcoholic fatty liver disease confirmed with imaging techniques.
Body Mass Index (BMI) of them is greater than 24.9 and lower than 40.
Exclusion Criteria
Alcohol consumption
Pregnant and lactating women
Any known forms of hepatic or metabolic disease except NAFLD, such as hereditary hemochromatosis, Wilson’s disease, cirosis, other metabolic disease
history of gastric bypass or intestine surgery
Taking hepatotoxic drugs such as calcium channel blocker, methotrexate, amiodarone, chloroquine and anti inflammatory drugs
Using antioxidant supplements
Hormone Therapy
Patients with a history of Cushing’s syndrome
renal failure
Participants with less than 80% are going to be excluded.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method iver enzymes (ALT, AST). Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Using Microgram/ml - laboratory kit.;Lipid profile (TG, HDL, Total cholestrol). Timepoint: The first day of the study and the last day of 8th week. Method of measurement: laboratory kit.;Liver steatosis index. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Sonography.;Fasting blood sugar. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: laboratory kit.;Total antioxidant capacity. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: laboratory kit.
- Secondary Outcome Measures
Name Time Method Waist to hip ratio. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Non-stretchable tape without any pressure.;Body Mass Index (BMI). Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Weight (kilograms) divided by the square of height (meters).;Sistolic and diastolic blood pressure. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: By mercury sphygmomanometer.