Effect of high dose vitamin D on blood glucose in critically ill patients
Phase 3
- Conditions
- Hyperglycemia.Elevated blood glucose level
- Registration Number
- IRCT2014061218069N1
- Lead Sponsor
- Vice Chancellor for Research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Critically ill patients aged between 18-65 years old with diagnosis of stress-induced hyperglycemia during the first 24 hours of intensive care unit (ICU) admission will be recruited.
Exclusion criteria:
Patients with following characteristics will be excluded: Diabetic patients, hemoglobin (Hbg) A1C>7.5, positive history of hypersensitivity to vitamin D or its analogues, hypercalcemia, any contraindication for intramuscular (IM) injection, current use of corticosteroids or any drugs affecting patients’ blood glucose.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma insulin. Timepoint: During 24 hours of ICU admission and 7 days after intervention. Method of measurement: Elisa kit.;Plasma glucose. Timepoint: During 24 hours of ICU admission and 7 days after intervention. Method of measurement: Elisa Kit.;Serum level of 25 (OH) vitamin D3. Timepoint: During 24 hours of ICU admission and 7 days after intervention. Method of measurement: Elisa kit.;Adiponectin. Timepoint: During 24 hours of ICU admission and 7 days after intervention. Method of measurement: Elisa kit.
- Secondary Outcome Measures
Name Time Method