The effect of vitamin D deficiency treatment on dyspnea severity in patients with COPD
Phase 2
- Conditions
- Chronic Obstructive Pulmonary Disease.Emphysema -Other specified chronic obstructive pulmonary disease-Chronic obstructive pulmonary disease, unspecified- -J43, J44.8
- Registration Number
- IRCT2017042919554N12
- Lead Sponsor
- Vice chancellor for research, Zanjan University of Medical Sciences.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion Criteria: Outpatients suffering from COPD who haven’t had COPD exacerbation in last 2 weeks; serum vitamin D level less than 30 ng / dl; written consent for participating in the study.
Exclusion Criteria
liver problems (LFT equal to or more than 2 times more than normal); renal failure (GFR<60); Granulomatous diseases (including tuberculosis, sarcoidosis); malnutrition; malabsorption (including IBD and Celiac); any types of cancer; parathyroid disease.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Forced expiratory volume (FEV1). Timepoint: Before the intervention and three months after the end of intervention. Method of measurement: spirometery.;Forced expiratory volume 1/ Forced vital capacity(FEV1/FVC). Timepoint: Before the intervention and three months after the end of intervention. Method of measurement: Spirometry.
- Secondary Outcome Measures
Name Time Method Severity of Dyspnea. Timepoint: Before the intervention and three months after the end of intervention. Method of measurement: MRC Dyspnoea Scale.;Weight. Timepoint: Before the intervention and three months after the end of intervention. Method of measurement: Scale.