Effects of vitamin D on insulin resistance and endothelial dysfunction in diabetic patients with ischemic heart disease

Recruiting

• Conditions: Diabetes; ischemic heart disease; Metabolic and Endocrine - Diabetes; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12614000529640
• Lead Sponsor: Shahid Beheshti University of medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-05-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients with diagnosis of type 2 Diabetes mellitus on the basis of ADA criteria and ischemic heart disease based on angiography results

Exclusion Criteria

1. History of hypersensivity to Vitamin D
2. Renal failure
3.Hypercalcemia
4. Pregnant women
5. Lactating women
6.Hepatic failure (Child-Pugh B and C)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
owering Inflammatory marker, hs-CRP, based on measuring serum level[2 month];Improving insulin resistance based on HOMA-IR model[2 month]

Secondary Outcome Measures

Name	Time	Method
Alleviation of endothelial function based on ICAM-1 and VCAM-1 measured level[2 month]