Oculomotor Disorders: Experimental and Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Visual Functions
研究概览
简要总结
Amblyopia and strabismus are characterized by a reduction in visual acuity, contrast sensitivity, grating acuity, vernier acuity, reading difficulties and binocular visual function deficits. Treated patients have residual visual function deficits. The purpose of the current study is to quantify various visual functions in amblyopic and strabismic participants at baseline, during and at the completion of treatment.
详细描述
To examine the response of therapy on visual functions in amblyopic and strabismic participants.
The following visual functions will be measured prior to treatment. Eye movements, contrast sensitivity, grating acuity, visual acuity, vernier acuity, binocular visual functions, reading and visual scanning will be measured. The testing will comprise of one or more of the above paradigms depending on participant's cooperation and understanding as majority of the study participants will be children. The above measurements will be repeated during amblyopia therapy ( which comprises of glasses, patching and/or atropine eye drops) and at the completion of treatment. For participants with strabismus requiring strabismus surgery the measurements will be repeated after strabismus surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Months 至 90 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •History of amblyopia or presence of amblyogenic risk factors.
排除标准
- •History of neurologic disorders
研究组 & 干预措施
Amblyopia
Clinical diagnosis of amblyopia
干预措施: Patching therapy, Glasses (Behavioral)
Control subjects
Subjects who state they have no eye or neurologic problems or disease other than perhaps wearing glasses or contact lenses and upon review of medical history.
结局指标
主要结局
Visual Functions
时间窗: 0-3 years depending on duration of treatment
contrast sensitivity
Visual functions
时间窗: 0-3 years depending on duration of treatment
vernier acuity
次要结局
未报告次要终点
研究者
Fatema Ghasia
Associate Staff
The Cleveland Clinic
