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临床试验/NCT04310241
NCT04310241招募中不适用

Oculomotor Disorders: Experimental and Clinical Study

The Cleveland Clinic1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2020年2月21日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
150
试验地点
1
主要终点
Visual Functions

研究概览

简要总结

Amblyopia and strabismus are characterized by a reduction in visual acuity, contrast sensitivity, grating acuity, vernier acuity, reading difficulties and binocular visual function deficits. Treated patients have residual visual function deficits. The purpose of the current study is to quantify various visual functions in amblyopic and strabismic participants at baseline, during and at the completion of treatment.

详细描述

To examine the response of therapy on visual functions in amblyopic and strabismic participants.

The following visual functions will be measured prior to treatment. Eye movements, contrast sensitivity, grating acuity, visual acuity, vernier acuity, binocular visual functions, reading and visual scanning will be measured. The testing will comprise of one or more of the above paradigms depending on participant's cooperation and understanding as majority of the study participants will be children. The above measurements will be repeated during amblyopia therapy ( which comprises of glasses, patching and/or atropine eye drops) and at the completion of treatment. For participants with strabismus requiring strabismus surgery the measurements will be repeated after strabismus surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
6 Months 至 90 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •History of amblyopia or presence of amblyogenic risk factors.

排除标准

  • •History of neurologic disorders

研究组 & 干预措施

Amblyopia

Clinical diagnosis of amblyopia

干预措施: Patching therapy, Glasses (Behavioral)

Control subjects

Subjects who state they have no eye or neurologic problems or disease other than perhaps wearing glasses or contact lenses and upon review of medical history.

结局指标

主要结局

Visual Functions

时间窗: 0-3 years depending on duration of treatment

contrast sensitivity

Visual functions

时间窗: 0-3 years depending on duration of treatment

vernier acuity

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fatema Ghasia

Associate Staff

The Cleveland Clinic

研究点 (1)

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