Study to find the suitable induction agent for stable haemodynamics during surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2018/12/016720
- Lead Sponsor
- Department of Anesthesiology and Critical Care BATRA HOSPITAL MEDICAL RESEARCH CENTRE NEW DELHI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Age group 18-65 years.
2. Either sex
3. ASA status I&II
4. BMI of 18.5-30.
5. Patients posted for elective surgeries under general anaesthesia
Exclusion Criteria
1. Hypertension and IHD
2. Morbid obesity
3. H/O chronic pain.
4. Patients on drugs like β blockers or calcium channel blockers.
5. Pregnant or lactating women
6. H/O Substance abuse
7. Patients with psychological disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Combining propofol and ketamine results in the hypotension and bradycardia caused by <br/ ><br>propofol getting counteracted by hypertension and tachycardia caused by Ketamine, thereby <br/ ><br>resulting in better hemodynamic stability on induction[9]. Ketamine reduces the pain on injection <br/ ><br>of propofol which in turn attenuates the emetic effect and emergence reaction caused by <br/ ><br>ketamine. <br/ ><br>Timepoint: before induction at 1 minute 2 minutes and 3 minutes <br/ ><br> <br/ ><br>After intubation at 2 minutes 5 minutes and 10 minutes
- Secondary Outcome Measures
Name Time Method post op emergence, nausea and vomitingTimepoint: immediate post op and 1st and 2nd hour post operation