Study to find the suitable mixing ratio of anesthetic agents Ketamine and Propofol for stable hemodynamic parameters like Blood pressure and Heart rate during surgery
Not Applicable
- Conditions
- Health Condition 1: D169- Benign neoplasm of bone and articular cartilage, unspecifiedHealth Condition 2: D249- Benign neoplasm of unspecified breastHealth Condition 3: K801- Calculus of gallbladder with othercholecystitisHealth Condition 4: M169- Osteoarthritis of hip, unspecifiedHealth Condition 5: N648- Other specified disorders of breastHealth Condition 6: K429- Umbilical hernia without obstruction or gangreneHealth Condition 7: K409- Unilateral inguinal hernia, without obstruction or gangrene
- Registration Number
- CTRI/2023/11/060040
- Lead Sponsor
- ok Nayak and associated hospitals
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adult patients, requiring elective surgery under general anesthesia with proseal LMA insertion.
2.Patients fulfilling ASA physical status I & II.
3.Age 20 – 60 years old adults.
Exclusion Criteria
1.Patients requiring rapid sequence induction
2.Patients having Cardiovascular, neurological and psychiatric disorders.
3.History of hypertension, diabetes mellitus.
4.Pregnant or lactating women.
5.Anticipated difficult airway.
6.Any known contraindications to ketamine or propofol.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effect of different ratios of ketamine propofol induction dose on the mean arterial pressure (MAP) after induction.Timepoint: 0 1 2 3 4 5 6 7 8 9 10 minutes after induction
- Secondary Outcome Measures
Name Time Method Incidence of postoperative emergence delirium.Timepoint: after completion of surgery;Postoperative nausea vomiting after end of surgery.Timepoint: 2 4 6 hours after surgery;The effect of different ratios of ketamine propofol induction dose on systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR).Timepoint: 1 2 3 4 5 6 7 8 9 10 minutes after induction