Examining the impact of sleep restriction on reward learning

Not Applicable

Completed

• Conditions: Sleep restriction; Mental Health - Other mental health disorders; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12623000181606
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-21
• Study Completion: 2023-12-05
• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

Healthy adults
- Aged between 18-39 years
- Fluent in English

Exclusion Criteria

- Any history or current serious medical (e.g., autoimmune disorders, inflammatory disorders, epilepsy, migraine, neurological disorders, colour blindness, eye disorders/diseases, or cancer), sleep, or psychiatric diagnoses
- Family history of mood or psychotic disorders
- Atypical sleep schedule (defined as a regular bedtime NOT between 10pm-12:30am or wake time NOT between 6am and 9am or a total sleep time more than 9 hours or less than 7 hours).
- A current or past smoker (within last year)
- Any illicit/recreational use of drug or medications (including prescription medications used outside of the prescribed use) within the past 3 months
- Taking psychotropic (anti-depressants, antipsychotics, and mood stabilisers), sleep or pain medications
- A moderate to severe traumatic brain injury (i.e., head injury accompanied by loss of
consciousness > 30 minutes and/or altered mental state > 24 hours)
- An average daily consumption of more than 400mg caffeine within the past 3 months.
- An average weekly consumption of more than 10 standard alcoholic drinks per week or more than 6 drinks per day, within the past 3 months.
- Any shift work within the past 3 months, defined as any work undertaken after 10pm and/or before 6am
- A BMI of <18.5 or >30
- Insufficient fluency in English to understand tasks and questionnaires
- No computer/laptop or internet connection to complete remote cognitive testing

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Probabilistic Reward Task - Response Bias <br><br>A response bias provides an index of the participants’ systematic preference for the response paired with the more frequent reward. <br><br>[ 2 Hours Post-intervention];Two-Step Task - Trial-by-Trial Behavioural Adjustment <br>Behavioural data will examine learning strategies employed, by examining the effects of transition type (common or rare) and reward (reward or no reward) on their subsequent first-stage choices (stay or switch). [ 2 Hours Post-intervention];Monetary Incentive Delay - Reaction Time<br>Overall mean response latency (in ms) for rewarded vs. non-rewarded trials, and across trials (measure of rate of learning). Response latency will be recorded by the task software. <br>[ 2 Hours Post-intervention]