Influence of sleep restriction on health, and analysis of the effect of the weekend catch-up sleep
- Conditions
- Prevention of intermediate chronic disease phenotypes in the general populationNot Applicable
- Registration Number
- ISRCTN14779364
- Lead Sponsor
- niversity of Valencia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 45
1. Volunteers recruited from the general population
2. Adults between 18 and 60 years old
3. BMI between 20 and 33 kg/m²
4. Habitual good sleepers (7-9 h/nights)
5. Intermediate chronotype
1. Does not meet the inclusion criteria
2. Shift or rotating workers
3. Travelers across time zones during the month prior to the start of the study
4. Present the following situations: consumption of drugs and alcohol on a regular basis, treatment with anxiolytics, corticosteroids or hypnotics, pregnant women, lactating women or with hormonal treatment, infectious, neurological, psychological, renal or hepatic diseases, cancer or other relevant pathologies that could bias the study
5. Any other condition that may interfere with sleep
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Expression level (Clariom™ S Assays Human and RT-PCR) and methylation pattern measured using (Methylation EPIC 850K array and MALDI-TOF) after a sleep restriction period plus a weekend catch-up period compared to habitual sleep at baseline, 5 and 7 days
- Secondary Outcome Measures
Name Time Method