The Role of Mid-Life Adiposity in Functional Brain Connectivity
Terminated
- Conditions
- Alzheimer's Disease
- Registration Number
- NCT01777789
- Lead Sponsor
- Medical College of Wisconsin
- Brief Summary
The purpose of the study is to use functional MRI (fMRI) to measure brain connectivity in middle-aged individuals with different levels of body fat. The ultimate goal of this research is to develop an early diagnostic tool for Alzheimer's disease.
- Detailed Description
Participants will have one visit for:
* Blood draw
* Body composition scan
* Cognitive screen
* Neurological exam
* MRI scan
The visit will take approximately 3 hours.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- 45-65 years of age
- Normal memory
- Right-handed
- General good physical health
Exclusion Criteria
- History of stroke or neurological disease
- Seizures or head injury with loss of consciousness within the last five years
- Ferrous (magnetic) or electronic implants (due to the magnet in the MRI scanner)
- Claustrophobia
More detailed inclusion/exclusion criteria must be met in order to qualify for the study. The study coordinator will determine eligibility.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Brain connectivity measured by fMRI One visit
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Medical College of Wisconsin/Froedtert Hospital
🇺🇸Milwaukee, Wisconsin, United States