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Clinical Trials/NCT03421158
NCT03421158
Completed
Not Applicable

Comparing the Analgesic Effects of Four Non-pharmacological Interventions on Term Newborns Undergoing Heel Lance

Stanford University0 sites236 target enrollmentNovember 7, 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain
Sponsor
Stanford University
Enrollment
236
Primary Endpoint
Decrease in Neonatal Pain, Agitation and Sedation Scale (NPASS) scores for newborns receiving non-pharmacologic interventions
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The purpose of this study is to compare the analgesic effects of four non-pharmacological interventions: skin-to-skin contact, breastfeeding, oral sucrose and nonnutritive sucking in newborns receiving a heel lance procedure.

Detailed Description

This is an randomized control clinical study. study population is healthy term newborns.Patients were identified by chart review and consent was received by nurse researcher. Newborns were randomized into either the control group who received no pain intervention or the intervention group who received one of four non-pharmacological pain interventions: skin to skin contact, breastfeeding, oral sucrose, and nonnutritive sucking. A heel lance for newborn screen blood sampling was selected as a study procedure and performed by a hospital technician following standard protocol. Pain scoring was assessed by two research nurses after the hell lance and through the procedure. Neonatal Pain, Agitation and Sedation Scale (NPASS) was selected as a pain assessment tool for this study. The average pain score from two research nurses were used for statistical analysis.

Registry
clinicaltrials.gov
Start Date
November 7, 2014
End Date
August 31, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Annette Nasr

Clinical Assistant Professor, Pediatrics

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Gestational Age 38-40
  • 2.5-4.0kg
  • 24-48hours of age
  • Receiving heel lance procedure
  • Apgar\>7 at birth
  • NPASS\<3 at time of heel lance

Exclusion Criteria

  • Prior heel lance procedure
  • birth trauma
  • forceps or vacuum delivery
  • maternal drug abuse during delivery

Outcomes

Primary Outcomes

Decrease in Neonatal Pain, Agitation and Sedation Scale (NPASS) scores for newborns receiving non-pharmacologic interventions

Time Frame: 12 month

Neonatal Pain, Agitation and Sedation Scale (NPASS) measures both behavioral and physiological components of pain by evaluating five key elements, and scores pain from 0-10 (Patricia A. Hummel, 2004). The assessment criteria are crying irritability, behavior state, facial expression, extremities tone, and vital signs.

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